Sperm in the reproductive tract is liquid state of existence. When sperm from the penis mouth after injection, immediately become glue frozen form or condensation piece of sample ivory material, this time the sperm in semen contains within or attached to the surface, not free swimming, 5-45 minutes later, semen produce a kind of automatic liquefaction process makes gel liquefaction, into a thin flow of liquid. The agglutinate a liquefaction process is enzyme catalysis process. The seminal vesicle gland a protein kind material to form a gel form the kind material of matrix, and the secretion of prostate a fiber proteolytic enzymes involved in the liquefaction process, the enzyme can dissolve clots since. Someone has been isolated from semen a molecular weight for 33000 liquefaction factor.
This liquid a aggregation of semen liquefaction process a has certain significance. The liquid is beginning to sperm injection. Then form clots in semen to stay in the vagina for a long time, and make the sperm get enough rest and the can. Once the liquefaction, sperm will have enough energy to penetrate the cervix mucus, and to the depths of the genital tract continues to advance, eventually to fallopian tube. In rodents, such as rats have solidified glands, sperm injection immediately when condensation to form a vaginal plugs. Completely sealed in semen inside vagina, the second day vaginal plugs will to fall off.
When the prostate gland or the seminal vesicle inflammation in, as the protein hydrolysis enzyme secretion of lack of or damage, cause enzyme system of disorders, make some of the patients with semen 1 hour also not placed liquefaction, or liquefied is not complete, viscosity is too high. This is called semen liquefaction not, is a kind of pathological phenomena. In this case, the sperm can't transitions, nature can cause infertility. Therefore, the seminal vesicle glands and prostate disease is not the important reasons caused by liquefaction.
Through to the fresh semen of the change of the character of observation, easier to make the diagnosis of semen liquefaction not, even if the patient is not good judgment. Important is to find out the cause not liquefaction further reason.
Semen liquefaction method not treatment has the following kinds:
(1) thorough treatment of prostatitis, seminal vesicle gland infection such as primary lesions, resume their normal function.
(2) containing 4% alpha-amylase with the physiological saline wash before sex, vaginal, or in sexual intercourse after injection 1 ml in the vagina. Can also be the enzyme 50 mg intermingled with cocoa butter made within 3 cm long Suppository, before intercourse into the vagina. This method is because someone found observed with semen liquefaction saliva, and the effect of inspiration. Alpha-amylase has not only promote semen liquefaction, the influence of the sugar vaginal secretions or cervix, and still can become sperm activity energy source. So, this kind of method widely used.
(3) in the semen to join the essence of the normal pulp, prompting liquefaction. But first, to determine the seminal plasma excluding antisperm antibody, no infection, and with prior high-speed centrifuge, remove sediment and freeze-thaw three processing.
(4) will be put into a growing the semen of vessels, with 18, 19, with the needle syringe suction again and again, until the semen thin, again through two centrifugal, washing and will last a sperm to a certain amount of the cultures of the suspension for artificial insemination.
(5) if semen high viscosity, usable segmentation method ejaculation, head to three issue the semen stay inside vagina, immediately take the penis, will the rest of the semen to shoot on the outside. Because the semen containing mainly for seminal vesicle gland secretion, so high viscosity.
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